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FDA Actions
In this section: Drug to treat hypoactive sexual desire disorder in premenopausal women goes live; new drug available to prevent delayed phase chemotherapy-induced nausea and vomiting; DPP-4 inhibitors used to treat type 2 diabetes may cause severe and disabling joint pain; and evolocumab receives approval.
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Aspirin and NSAIDs Reduce Colorectal Cancer Risk
Long-term continuous use of low-dose aspirin and long-term use of non-aspirin nonsteroidal anti-inflammatories was associated with reduced colorectal cancer risk.
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Chronic Sinusitis Recognized as Inflammatory Disease
Evidence supports daily high-volume saline irrigation along with topical corticosteroids as first-line therapy.
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Liraglutide Effective for Weight Loss in Diabetics
Among overweight and obese participants with type 2 diabetes, use of subcutaneous liraglutide daily compared with placebo resulted in weight loss over 56 weeks.
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Rosacea is Associated with Cardiovascular Disease
While the mechanism for the relationship between rosacea and cardiovascular disease is ill-defined at this point, one postulate is that systemic inflammation, which has been shown to alter the ability of lipoproteins to remove cholesterol from circulation, might be at least part of the explanation.
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Approaches to PTSD in Veterans
Mindfulness-based stress reduction shows promise as a valuable intervention for PTSD patients.
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Cardiovascular Autonomic Neuropathy Occurs Earlier in Type 2 Diabetes
Study results suggest cardiovascular autonomic neuropathy (CAN) may occur quite early, but whether treatment of diabetes might alter the course of CAN remains unknown.
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Early Identification, Intensive Intervention for Diabetes Might Improve Cardiovascular Outcomes
Multifactorial trials in which blood pressure, lipids, weight, exercise, and glucose are concomitantly addressed have produced favorable CV risk reduction, but it becomes difficult to ascertain which component(s) of the multipronged intervention is most responsible for the beneficial outcomes.
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Reversing Anticoagulant Effect of Dabigatran
A tool for reversal of novel oral anticoagulant effects may soon be available.
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Likelihood of Occult Cancer Causing Unprovoked Deep Venous Thrombosis
The likelihood of identifying occult cancer in patients with new unprovoked deep venous thrombosis is not meaningfully enhanced by performing extended screening.